There are 2 main brain dopamine systems in the reward pathway that relate to happiness: The dopamine reward center in the front half of the nucleus accumbens of the basal ganglia (involved with seeking pleasure and addiction). Think of the dopamine reward system involved with wanting and desire. The dopamine control center that enhances the activity of the prefrontal cortex/orbitofrontal cortex and helps you think before you act and stop unhelpful behaviors. The dopamine control center is involv