Heart patients & Pain killers: The hidden risks Pain relievers like ibuprofen or naproxen may seem like a quick fix, but for people with heart problems, they can be risky. Certain pain medications can increase blood pressure and fluid retention, putting extra strain on the heart. They can also interfere with medications the patient is already taking to manage their heart condition. Explore safer alternatives for managing pain at 'Heal Your Heart'. | Heal Your Heart