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  1. Down syndrome - Symptoms and causes - Mayo Clinic

    Nov 12, 2024 · Down syndrome is a genetic condition caused when an unusual cell division results in an extra full or partial copy of chromosome 21. This extra genetic material causes the developmental …

  2. Down Syndrome: Symptoms & Causes - Cleveland Clinic

    Down syndrome occurs because of changes in the way cells in chromosome 21 divide. Every person with Down syndrome has an extra chromosome 21 in some or all of their cells.

  3. What causes Down syndrome? | NICHD - NICHD - Eunice Kennedy …

    Jun 11, 2012 · What causes Down syndrome? Down syndrome is caused by a random error in cell division that results in the presence of an extra copy of chromosome 21. The type of error is called …

  4. Down syndrome - Wikipedia

    Down syndrome or sometimes Down's syndrome, [12] also known as Trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. [3] . It is usually associated …

  5. Down Syndrome | Birth Defects | CDC

    Dec 26, 2024 · We do not know for sure why Down syndrome occurs or how many different factors play a role. We do know that some things can affect your risk of having a baby with Down syndrome.

  6. Down syndrome - Harvard Health

    Jun 25, 2025 · Down syndrome is a disorder caused by having an extra chromosome. Chromosomes are pieces of DNA that have the blueprint for the human body. Normally a person has two copies of …

  7. Down syndrome | Definition, Chromosome, Symptoms, Causes, & Life ...

    Nov 21, 2025 · Down syndrome, congenital disorder caused by the presence in the human genome of extra genetic material from chromosome 21. The affected individual may inherit an extra part of …

  8. Causes of Down Syndrome: Genetic Types, Risk Factors & Diagnosis

    Down syndrome is a genetic disorder that occurs when there is an extra copy—either partial or full—of chromosome 21. This additional genetic material alters the course of development and results in the …

  9. Down Syndrome: Causes, Symptoms, Diagnosis, and Treatment - WebMD

    Feb 23, 2024 · Down syndrome is a genetic condition that causes mild to significant physical and developmental problems. People with Down syndrome (DS) are born with an extra chromosome. …

  10. About Down Syndrome - National Human Genome Research Institute

    Jun 29, 2017 · Some people who have Down syndrome have low activity of the thyroid gland (hypothyroidism) - an organ in the lower neck that produces hormones. How is Down syndrome …