As for any formulation containing an ACEi or ARB, use of ENTRESTO together with aliskiren-containing drugs is contraindicated in patients with diabetes mellitus, whether Type or 2, or in patients with moderate to severe renal impairment, i.e., eGFR < 60 mL/min/1.73m2 (see WARNINGS AND PRECAUTIONS, General, and Renal, and DRUG INTERACTIONS) Pregnant and nursing women (see WARNINGS AND ...