A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...
Adenosine-to-Inosine (A-to-I) editing is an endogenous RNA modification in eukaryotes, catalyzed by adenosine deaminases acting on RNA (ADARs). This modification modulates the gene expression by ...
The fungal-derived meroterpenoid pyripyropene A exhibits significant biological activities, including potent inhibition of acyl-CoA:cholesterol acyltransferase (ACAT) and high insecticidal efficacy ...
Abstract: Recently, advances in single-cell sequencing (scRNAseq) technology have enabled large-scale transcriptome analysis with high efficiency and single-cell resolution. Clustering in scRNA-seq is ...
The Vision Center at Children’s Hospital Los Angeles is developing a protocol for a phase 1 clinical trial for the first gene therapy for boys with blue cone monochromacy, which impairs color vision ...
Cell clustering serves as a key task in transcriptomic data analysis, playing a crucial role in cell type annotation, marker gene identification, and the discovery of rare cell populations. With the ...
Traditional meta-analyses pool effect sizes across studies to improve statistical power. Likewise, there is growing interest in joint clustering across datasets to identify disease subtypes for bulk ...
Engineering Research Center of Industrial Microbiology (Ministry of Education), Fujian Normal University, Fuzhou 350117, People’s Republic of China College of Life Sciences, Fujian Normal University, ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results