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Genome‐, transcriptome‐ and proteome‐wide measurements provide insights into how biological systems are regulated. However, fundamental aspects relating to which human proteins exist, where they are ...
Cellular DNA barcoding has become a popular approach to study heterogeneity of cell populations and to identify clones with differential response to cellular stimuli. However, there is a lack of ...
Only about 5 years after the first preclinical proof of concept for gene therapy of otoferlin-related auditory synaptopathy (Al-Moyed et al, 2018; Akil et al, 2019), preliminary reports from several ...
The protein expression profile of ACE2, suggested as host receptor for SARS‐CoV‐2, is assessed in various human organs. Notably, limited ACE2 expression is observed in the respiratory system both on ...
Hypoxic-ischaemic encephalopathy (HIE) arises from diminished blood flow and oxygen to the neonatal brain during labor, leading to infant mortality or severe brain damage, with a global incidence of 1 ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The X10 expansion microscopy protocol ...
For decades microtubule-targeting agents (MTAs) have been a cornerstone of cancer treatment regimens and continue to be heavily employed as backbone chemotherapy in combination with new targeted ...
Immunocytokines, comprising various antibody formats and cytokines, have been reported for cancer therapy (Gout et al, 2022). Targeting efficacy was shown to be determined not only by the antibody but ...
Author Correction: SGK1 inhibition in glia ameliorates pathologies and symptoms in Parkinson disease animal models ...
We have cloned cDNAs for the human homologues of the yeast Dcp1 and Dcp2 factors involved in the major (5′–3′) and NMD mRNA decay pathways. While yeast Dcp1 has been reported to be the decapping ...
Clustered regularly interspaced short palindromic repeat (CRISPR) is a recently discovered adaptive prokaryotic immune system that provides acquired immunity against foreign nucleic acids by utilizing ...
Review Process Files De-emphasis of confidential comments Referee cross-commenting Co-review The EMBO Press journals use a fair and transparent process to rapidly publish important science.