Davante Adams’ injury opens the door for Puka Nacua to dominate in Week 16 fantasy football, with Colby Parkinson and Tutu Atwell emerging as Rams sleepers to monitor.

Detroit Lions offensive lineman Graham Glasgow (60), Detroit Lions running back David Montgomery (5), and Detroit Lions offensive lineman Tate Ratledge (69) during an NFL football game against the Los Angeles Rams on Sunday, Dec. 14, 2025 in Inglewood, Calif. (Jeff Nguyen/Detroit Lions via AP)

A 52-yard catch-and-run by St. Brown following the kickoff immediately put the Lions in Rams territory. This time, the Lions reached the endzone via an eight-yard touchdown pass from Goff to St. Brown to regain the lead 17-14 with 6:12 to go in the first half.

The Los Angeles Rams go up against the Detroit Lions in Week 15. How would a win extend their place as the number one team according to power rankings?

The Rams took out their frustration on the Cardinals with a 45-17 win on the road, bouncing back from last week's stunning loss.

Catch up on all the Los Angeles Rams news heading into Sunday's matchup with the Detroit Lions at SoFi Stadium.

The Los Angeles Rams host the Detroit Lions in Week 15 of the 2025 NFL season on Sunday. There are several ways fans can watch and stream Sunday's game.

The Lions have won the last two games in this series, but the Rams are 6-point favorites in the latest Lions vs. Rams odds from DraftKings. The over/under for total points scored is 54.5. Kickoff from SoFi Stadium in Los Angeles is set for 4:25 p.