Every cell in our body contains the same DNA, yet liver cells are different from brain cells, and skin cells differ from muscle cells. What determines these differences? It all comes down to gene ...

Researchers from Osaka University find that neuronal activity induces gene expression at the preprepared histone acetylation sites in the nucleus by influencing transcription factors and chromatin ...

The human genome contains approximately 1,600 types of transcription factors responsible for regulating gene activity across more than 400 tissue and cell types. Chromatin immunoprecipitation ...

Neuronal specification, expansion and differentiation are tightly regulated by the concerted actions of transcription and chromatin modifying factors that are recruited to regulatory elements in the ...

A robust and quantitative map links chromatin modification and gene expression of cells during zebrafish embryogenesis.

A recent study led to the development of a powerful epigenetic editing technology. The system unlocks the ability to precisely program chromatin modifications at any specific position in the genome, ...

Scientists have uncovered surprising ways transcription factors, the genetic switches for genes, regulate plant development. Their findings reveal how subtle changes in a lipid-binding region called ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...

When a salamander loses a leg, it grows back. When a human loses a finger, scar tissue fills the gap. The difference has ...

Why do brain disorders affect men and women differently? Researchers used RNA sequencing to identify 3,000 sex-biased genes ...