Biomolecular condensation has emerged as a unifying principle in cell biology, offering a compelling framework to explain the formation of diverse, dynamic, and often transient compartments observed ...

How do evolutionarily conserved pathogen effectors maintain structural stability while engaging diverse host targets? In a new study published in Molecular Plant Microbe Interactions, researchers at ...

"The protein folding problem--the way in which unfolded proteins manage to reach their native, three-dimensional, functional form--has become a central focus for many scientists," declares Walter ...

Yuan He aims to understand how cells read and repair their genomes. His research encompasses two primary areas: transcription, in which genetic information is copied from DNA into messenger RNA, and ...

The Zheng Laboratory investigates the structural and functional properties of disease-related membrane proteins from prokaryotes and eukaryotes, primarily focusing on characterizing these proteins ...

Cryo-electron microscopy (cryo-EM) has revolutionalized our understanding of the intricate molecular machinery that governs life. It has elucidated the three-dimensional (3D) structure of biological ...

Structural biology--the study of the three-dimensional shapes of biological macromolecules--has always been a facet of biological research, from the detection of cells in the earliest days of ...

Two key protein structures in the body are being visualized for the first time, thanks in part to the latest technology in the University of Cincinnati’s Center for Advanced Structural Biology — ...

A microscopic image shows small red centers connected by networks of branched and straight filaments. The team mixed purified actin monomers with precise concentrations of two nucleation-promoting ...

Despite decades of study, a pharmacopoeia of medicines, and untold millions in pharmaceutical research, heart disease remains the leading cause of death around the world. Excess cholesterol in ...