Scientists from Johns Hopkins and the University of Wisconsin have discovered that a protein called Sir2, which is found in nearly all living cells, has a new function that might help explain how ...

The enzyme sirtuin 6, or SIRT6, serves many key biological functions in regulating genome stability, DNA repair, metabolism and longevity, but how its multiple enzyme activities relate to its various ...

Sirtuins are NAD +-dependent enzymes that modulate the activities of target proteins, mediate changes in the metabolic status of cells and regulate diseases of ageing, including neurodegeneration, ...

Naturally occurring pigments in berries, also known as anthocyanins, increase the function of the sirtuin 6 enzyme in cancer cells, a new study from the University of Eastern Finland shows. The ...