The association between migraine with aura and persistent foramen ovale (PFO), as well as other right-to-left shunts, is described. A hypothesis that might explain this association is discussed.

To the Editor: In the Clinical Practice article on cryptogenic stroke by Saver (May 26 issue), 1 the importance of transcranial Doppler ultrasonography was underappreciated. My colleagues and I, 2 as ...

IN addition to congenital heart disease, with right-to-left shunts, and chronic lung disease, cyanosis in babies can be caused by methemoglobinemia. The congenital variety, of course, is lifelong, but ...