Scientists at the Yong Loo Lin School of Medicine, (NUS Medicine), have identified a molecular switch that helps aging brains ...

Researchers at the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have found that a key ...

Overcoming tumor resistance to chemotherapy drugs has long been a challenge for oncology clinicians and researchers. Now, a new study suggests that blocking a key protein, p300, may force damaged ...

The IDR in TAF2 steers the protein away from active gene promoters, where it participates in transcription initiation, to nuclear speckles — liquid-like compartments that concentrate factors for RNA ...

Delivery of therapeutic proteins or other intracellular materials has been a long-standing challenge for translational medical researchers. Effective strategies can present a powerful tool for many ...

A new mouse study found that unrepaired DNA-protein crosslinks activate inflammatory signaling pathways that trigger early aging disorders.

This image illustrates the process of gene transcription within a cell. The DNA double helix unwinds to expose a specific sequence, allowing RNA polymerase to synthesize a complementary pre-mRNA ...

DNA can be regarded as an extensive library that contains all genetic information. Cells do not utilize this information simultaneously.