In this valuable study, the authors develop new approaches to investigate mRNA imprinting, a phenomenon in which RNA-protein complexes form in the nucleus to influence the fate of transcripts in the ...

The nucleolus serves as the central hub for ribosomal DNA (rDNA) transcription and ribosome biogenesis, processes essential for protein synthesis and cellular proliferation. rDNA transcription is ...

This image highlights two alternatives for the ribosome to be recruited to an mRNA that is still being synthesized by RNA polymerase (RNAP). RNAP (left, red) can directly deliver the mRNA to the entry ...

Rush hour never ceases at the nucleus’ border. Gene products begin their lives in the nucleus as strands of mRNA that ship out into the cytoplasm, where they serve as templates for protein synthesis.

A study in Developmental Cell reveals that epidermal cells preload their perimeters with ribosomes and specific mRNAs, enabling near-instant protein synthesis when the skin barrier is breached. This ...