Peripheral sensitization refers to the lowering of the threshold of excitability of sensory neurons, which leads to an amplified reaction to a specific external stimulus. Sensitization can be mediated ...
Osteoarthritis pain arises from a dynamic interplay of peripheral and central processes that amplify nociceptive signalling beyond the extent of joint damage alone. At the periphery, local ...
Central sensitization syndrome can cause the brain to overreact to harmless stimulation, leading to intense pain feelings. Typically, the CNS sends sensory signals to the brain. The brain accurately ...
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