De novo peptide sequencing from tandem mass spectra imposes no prior restrictions on the space of possible amino acid sequences, thus allowing for the identification of peptides or proteins outside ...

Despite advances in mass spectrometry and emerging single-molecule approaches, sequencing peptides at the single-molecule level remains a central challenge in proteomics. Here we present a ‘reverse ...

Our food and our bodies are full of tiny protein fragments called peptides. These small chains of amino acids act as biological messengers, influencing processes ranging from sensory perception to ...

Proteins, one of the smallest building blocks of life on Earth, hold promise for answering some of biology's biggest questions. Consisting of amino acids strung together into peptide chains, these ...