The San Francisco 49ers defense struggled some against the Tennessee Titans, but their offense had a huge day to mark the ...

SANTA CLARA, Calif. — Brock Purdy threw three touchdown passes and the San Francisco 49ers started the stretch run of their ...

The Tennessee Titans, led by quarterback Cam Ward, face the San Francisco 49ers, led by quarterback Brock Purdy, on Sunday, ...

Purdy was pushing the ball to all corners of the field, picking up first downs — and more — with his scrambling ability, and ...

McCaffrey's late back issue raises questions, while Aiyuk's season-ending move on reserve/left squad list signals a dramatic ...

Brock Purdy threw three touchdown passes and the San Francisco 49ers started the stretch run of their season with a 37-24 ...

"It's actually hard to fathom how much money Brandon Aiyuk is giving away." ...

The San Francisco 49ers placed Brandon Aiyuk on the reserve/left squad list on Saturday, which officially ends his season, ...

The Tennessee Titans are injured beyond belief against the San Francisco 49ers.

The San Francisco 49ers added All-Pro running back Christian McCaffrey to their injury report Saturday with a back injury, ...

Listed as inactive for the 49ers were wide receiver Jordan Watkins, running back Jordan James, linebacker Nick Martin, ...

It's the first career receiving touchdown for the Tennessee Titans star against the San Francisco 49ers.