The nicotinic acetylcholine receptor (AChR) is assembled on the cell surface from multiple subunits produced in the endoplasmic reticulum (ER), but how these mechanisms are controlled has been unclear ...
It has been amply proven that smoking can cause serious diseases such as emphysema and cancer. A new study, however, shows that pharmacological stimulation of a specific type of nicotinic receptor in ...
ADELAIDE, Australia, and CAMBRIDGE, Mass., Sept. 14, 2023 (GLOBE NEWSWIRE) -- Bionomics Limited (BNOX) (Bionomics or Company), a clinical-stage biotechnology company developing novel, first-in-class, ...
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the accumulation of misfolded ...
Novel non-addicting analgetic therapies are urgently needed to reduce the use of opiates as painkillers. With the recent discovery that nicotinic acetylcholine receptors (nAChRs) in the immune system ...
Rare genetic variants in a little-studied nicotine receptor subunit are linked to markedly lower cigarette consumption, pointing to a potential new biological pathway for reducing smoking intensity ...
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