Nephrin is a major component of the glomerular filtration barrier. Mutations in the nephrin gene (NPHS1) are responsible for congenital nephrotic syndrome of the Finnish type (NPHS1). Nephrin was at ...

A groundbreaking study, presented today at the 61st ERA Congress, has uncovered a significant breakthrough in the diagnosis and monitoring of kidney diseases associated with nephrotic syndrome. Using ...

A study, presented at the 61st ERA Congress, has uncovered a significant breakthrough in the diagnosis and monitoring of kidney diseases associated with nephrotic syndrome. The study is also published ...

Please provide your email address to receive an email when new articles are posted on . Findings of minimal change disease in adults and children with autoantibodies targeting nephrin supports prior ...

(Upper panel) Normal podocytes: Ephrin-B1 at slit diaphragm interacts with nephrin via the extracellular site and with Par6 via the cytoplasmic site. (Lower panel) Podocytes stimulated by anti-nephrin ...

A group led by the Department of Cell Biology at the Kidney Research Center, Niigata University revealed that elevated activity of cdc42 is a critical initiation event leading to proteinuria, and ...

STOCKHOLM — People with difficult to diagnose kidney diseases linked to nephrotic syndrome show uniquely high levels of antinephrin autoantibodies, suggesting a novel biomarker and breakthrough ...

Using a hybrid technique, researchers identified anti-nephrin autoantibodies as a reliable biomarker for tracking disease progression, opening new avenues for personalised treatment approaches.