Chemical structure of (-)-naloxone and (+)-naloxone enantiomers. Ki of (-)-naloxone for antagonizing opioid receptors is in the 1 nM range whereas (+)-naloxone has a very low affinity for opioid ...

In 1971, almost half a century ago, emergency rooms started reversing opioid overdoses using a medicine called naloxone. It's generic today, and industry insiders told us it can cost as little as a ...

Two advisory committees to the US Food and Drug Administration have voted unanimously to recommend that a nasal spray version of the opioid overdose antidote, naloxone (also called Narcan), be made ...

Naloxone – also known as Narcan – is a medication that can reverse the effects of an opioid overdose. This includes heroin, fentanyl, and some types of painkillers. Paramedics and emergency room ...

Shane Darke does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their ...

After years of continuously rising opioid overdoses, the US Centers for Disease Control and Prevention reported that overdose deaths decreased 3% in 2023, the first annual decrease since 2018. A new ...