Autistic adults show reduced availability of a key glutamate receptor, mGlu5, across widespread brain regions.

Researchers have discovered a molecular difference in the brains of autistic people compared to neurotypical people, a finding that has implications for intervention.

A new protein sensor lets researchers see incoming brain signals, revealing how neurons process information tied to memory ...

Glutamate receptors are the primary mediators of excitatory transmission in the central nervous system and are mostly located on the dendrites of postsynaptic neuronal and glial cells, such as ...

To study how a key chemical neuromodulator affects signaling in the brain's cortex, Garrett Neske, PhD, has received a three-year, $300,000 grant from the Whitehall Foundation, a nonprofit ...

Control of the glutamate time course in the synapse is crucial for excitatory transmission. This process is mainly ensured by astrocytic transporters, high expression of which is essential to ...

Philadelphia, May 11, 2023 – Dysregulation of the dopamine neurotransmitter system has long been associated with schizophrenia and other forms of psychosis, but recently researchers have begun to ...

In the intricate chemical symphony of the brain, glutamate stands as the principal conductor. As the brain's most abundant excitatory neurotransmitter, glutamate facilitates our ability to learn, form ...

Using in vivo imaging technology, investigators at the University of Utah and the University of Padua have identified a new signaling mechanism for glutamate that was linked to the onset of spreading ...

Scientists at the University of Cambridge have used powerful new brain imaging techniques to reveal a neurochemical imbalance within specific brain areas in patients with obsessive-compulsive disorder ...