A cell-free genomics approach silences cellular noise and reveals transcription drivers, improving our understanding of a ...

Every cell in our body contains the same DNA, yet liver cells are different from brain cells, and skin cells differ from muscle cells. What determines these differences? It all comes down to gene ...

In a new study published in Cell Reports, researchers at the University of Freiburg detail how a disordered protein fragment connects two key stages of gene expression: transcription and RNA editing.

To support drug discovery, a new study has revealed fundamental features of the transcription cycle in the bacteria that causes tuberculosis.

A newly released publication examines how deuterium concentration may influence gene activity in lung cancer cells. The study explores how shifts in this ...

Timing of gene expression Demonstrating their technique in mouse embryonic stem cells, the researchers found that they could calculate approximately when a particular region starts to be transcribed, ...

Scientists usually study the molecular machinery that controls gene expression from the perspective of a linear, two-dimensional genome—even though DNA and its bound proteins function in three ...

Recent studies reveal that changes in gene regulation, not just gene sequences, are crucial for the evolution of animal ...

During development, many crucial genes help organisms form properly. One of those genes is myogenic determination gene number 1 (MyoD), which can exert a powerful influence as a “genome organizer." It ...

Like islands scattered across a vast intergenic sea, the nearly 20,000 protein-coding genes within the human genome represent a mere 2 percent of its 3 billion base pairs. When, where, and to what ...