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Researchers create stable chiral molecules with novel stereogenic centers for future medicines
The new stereogenic centers developed by the Geneva team should enable the design of stable, controlled, three-dimensional chiral molecules. These structures open up new possibilities for drug design ...
The new method enables what had been impossible except in narrow cases: creating a center of chiral asymmetry at a hard-to-reach position called the “gamma” position on a cyclic carboxylic acid.
LA JOLLA, CA—Scripps Research chemists have accomplished a long elusive feat in synthetic chemistry: the invention of a broadly useful method for constructing “gamma chiral centers” on simple starting ...
Chemists have synthesized the first stable molecule whose chirality is solely attributed to a stereogenic oxygen, according to a new study (Nature 2023, DOI: 10.1038/s41586-023-05719-z). Though carbon ...
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