When we discuss bacterial infections, we often think of exotoxins—those soluble proteins actively secreted by bacteria—while overlooking endotoxins, which are more insidious but equally dangerous.

Endotoxin refers to a component of the outer cell membrane of Gram-negative bacteria called lipopolysaccharide (LPS). LPS is the biologically active portion of naturally occurring endotoxin complexes.

For over a century, one invisible chemical has misled scientists, contaminated breakthrough experiments, and disrupted drug development. In this video, we uncover the hidden story of endotoxins—from ...

BRD is often framed as stress, viruses and bacteria. Managing inflammation tied to endotoxin helps explain why some cattle recover faster than others ...

Ensuring the safety of medical products, such as drugs, biologics, or devices, requires careful testing for contaminants. Bacterial endotoxins are a major concern for pharmaceutical manufacturers ...

Escherichia coli is widely considered the most cost-effective bacterial system for recombinant protein expression. Consequently, it is broadly used. Nonetheless, it has its limitations as an ...

Surf on a beach at sunset features a horseshoe crab upside down in the water and several others nearby. Regulatory changes may make the pharmaceutical industry less reliant on horseshoe crabs for ...