While resurrected animal species grab headlines, Colossal’s behind-the-scenes R&D may be poised to make an impact for humans as well.

Call them dire wolves. Don’t call them dire wolves. Colossal Biosciences, the biotechnology company from Dallas, Texas, that wants to de-extinct the woolly mammoth and dodo, doesn’t care what you call ...

The dire wolf, an ancient species that went extinct more than 10,000 years ago, has been revived in a “de-extinction” according to scientists. On Monday (7 April), Texas-based Colossal Biosciences ...

Romulus and Remus are doing what puppies do: chasing, tussling, nipping, nuzzling. But there’s something very un-puppylike about the snowy white 6-month olds—their size, for starters. At their young ...

The Dallas-headquartered biotech company revealed in April 2025 that two separate dire wolf litters had been born: The two ...

Creating the dire wolves called for making just 20 edits in 14 genes in the common gray wolf, but those tweaks gave rise to a host of differences, including Romulus’ and Remus’ white coat, larger size ...