Desensitization is an important mechanism curtailing the activity of ligand-gated ion channels (LGICs). Although the structural basis of desensitization is not fully resolved, it is thought to be ...
The GluA2 receptor in the present study contained residues K393 to K817, which make up the LBD, the LBD–TMD linkers and the TMD (Fig. 1). Its structure in the resting state (that is, with an ...
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