Inside each human cell, about 2 meters (6.6 feet) of genomic DNA must be accurately copied and equally transmitted to two ...

As humans get older, their brains undergo various changes that can affect mental functions. The cells known to be affected by aging include microglia, the primary immune cells in the brain and spinal ...

After an injury, DNA not only changes its activity but also the way it is organized spatially within the cell nucleus. In ...

Researchers show that long-range chromatin loops help control tissue regeneration, revealing a direct role for 3D genome ...

Researchers find >1,200 autism risk genes converge into two opposing molecular states in the brain, influencing responses to experimental drugs.

High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact within these droplet-like structures. The findings connect molecular ...

The human genome is about two meters long, yet it is folded inside a cell nucleus only about 10 micrometers in diameter.

Discover how single-molecule Fiber-seq is revealing unexpected mechanisms of transcription factor regulation, chromatin ...

Chromatin's structure plays an important regulatory role in DNA template-dependent processes including transcription, replication, recombination, repair, segregation, chromosomal stability, cell cycle ...

If I asked you, dear reader, to come up with a shortlist of the most monumental scientific achievements of the last century, chances are the Human Genome Project (HGP) would appear somewhere on that ...