Every time our body encounters a new disease-causing agent, a crucial defense system called adaptive immunity comes into play ...

Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...

A research team of the University Medical Center Mainz has succeeded in observing for the first time how G protein-coupled ...

Scientists are aiming to determine the composition and topology of physiological Ashwell-Morell receptor ligands. Their findings will help uncover the receptor's still-hidden secrets. After earning ...

Adhesion G protein-coupled receptors have a large extracellular region (shown in green and orange) that extends into space outside the cell. Almost 35% of drugs approved by the Food and Drug ...

Many people are familiar with histamine, a biological molecule that serves as a key driver of allergic reactions and other ...

A new study shows how the single-molecule organization of receptors in a cellular context determines the function of antibodies, opening up new pathways for the development of cancer immunotherapies.

Receptors are cellular components that trigger internal changes based on external signals. Researchers have built a new synthetic receptor with incredibly broad potential to program cell activity, ...

New Cell-Based Assays Support Drug Discovery Across the Amylin Receptor Family STATE COLLEGE, PA, UNITED STATES, ...

Scientists at École Polytechnique Fédérale Lausanne (EPFL), and at UNIL-CHUV, University Hospital Lausanne (CHUV) and University of Lausanne (UNIL) have developed a computational method to create ...