A research team led by Prof. LIU Qingsong from the Hefei Institutes of Physical Science of the Chinese Academy of Science has developed IHMT-15130, a selective and irreversible inhibitor of Bone ...

Cardiac hypertrophy is a growth response of the heart to increased hemodynamic demand or damage. Accompanying this heart enlargement is a remodeling of Ca²⁺ signaling. Due to its fundamental role in ...

Heart failure is the terminal stage of various cardiovascular diseases, usually characterized by pathological myocardial hypertrophy. So far, the pathogenesis of heart failure is not fully understood.

When the workload on the heart increases, the ventricular wall may thicken too, known as cardiac hypertrophy. This is an adaptive response that reduces pressure on the heart and maintains the activity ...

Cardiac hypertrophy is a main contributor to heart failure, where therapeutic options are limited. Increasing evidence exists regarding up-regulation of histone lysine-specific demethylase 4A (KDM4A) ...

A groundbreaking European study published in the European Heart Journal has uncovered a sobering truth: female bodybuilding ...

Historical rationing may have had cardioprotective effects ...

Preserved systolic and diastolic cardiac function is seen in TREK-1-KO animals in response to pathological pressure overload stress, which may cause enhanced concentric hypertrophy and alterations in ...

An autopsy result has revealed the cause of death for Cincinnati Bearcats offensive lineman Jeremiah Kelly, who died in April at the age of 18. Kelly died of a heart condition known as cardiac ...