In adults with stage IIIb–IV chronic kidney disease, the constipation drug lubiprostone did not reduce gut-derived uremic ...

Compared with using stool softeners, taking lubiprostone was significantly associated with lower risks of a composite adverse kidney outcome and steeper eGFR decline. The risk for kidney function ...

When a phase two clinical trial from Japan suggested that a common constipation medicine might slow the progression of ...

Professor Takaaki Abe and his team discovered that a medicine called lubiprostone, which is normally used to treat ...

Chronic kidney disease (CKD) is a progressive condition in which the kidneys are damaged and can’t filter blood effectively. This can eventually lead to a buildup of waste and fluid in the body. In ...