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DMD gene therapy Elevidys linked to new liver failure case
Liver damage is a well-recognised complication of gene therapies based on adeno-associated virus (AAV) vectors, and other drugs – including Novartis' spinal muscular atrophy (SMA) treatment Zolgensma (onasemnogene abeparvovec) and Astellas' X-linked myotubular myopathy therapy AT132 – have been associated with deaths due to acute liver failure.
Sarepta Shares Dive on Second Fatal Liver Failure Tied to Elevidys
Sarepta Therapeutics shares dived 42% in premarket trading after the company disclosed a second reported case of acute liver failure that resulted in a death tied to its Duchenne muscular dystrophy treatment Elevidys. Shares were trading around $20.61. The stock is down 70% on the year.
Follow-up reached a median 5.5 years overall. Adverse liver outcomes in question counted cirrhosis, decompensation, ...
Liver illnesses can arise from a range of causes, such as viral infections, chronic alcohol consumption, obesity, and ...
Learn about 5 liver infections that can hide in your body for decades without symptoms. Discover warning signs and prevention ...
The Global Liver Institute urges worldwide integration of liver health into diabetes and obesity care as steatotic liver ...
Find Early Signs Of Liver Disease Latest News, Videos & Pictures on Early Signs Of Liver Disease and see latest updates, news, information from NDTV.COM. Explore more on Early Signs Of Liver Disease.
When the liver is damaged, bilirubin builds up in the bloodstream and causes the skin and the whites of the eyes to turn yellow. This yellow color is often first seen on the face, hands, and feet.
Excess fat mass estimated by waist circumference-to-height ratio predicts the risk of liver damage better than body mass ...
Q. Monsoon often triggers a spike in gastrointestinal infections. What are the most common liver-related complications ...
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