Shota Imanaga pitched one-run ball into the eighth inning in Chicago's home opener at Wrigley Field, and the Cubs handed San Diego its first loss with a 3-1 victory over the Padres on Friday.

Shota Imanaga threw 7 1/3 quality innings and Justin Turner delivered the go-ahead RBI single on Friday to propel the Chicago Cubs to a 3-1 victory over the visiting San Diego Padres.

The frigid Friday afternoon game was the Cubs’ 150th home opener and their 110th at Wrigley Field, and it brought to an end the best start to any of the Padres’ 57 seasons after Cubs closer Ryan Pressly struck out Jake Cronenworth looking with runners on second and third to end the game.

Preview the April 5 matchup between the Chicago Cubs and San Diego Padres with recent trends, how to watch, livestream info, and more.

Preview the April 5 matchup between the Chicago Cubs and San Diego Padres with odds over/under, game spread, betting lines and more.

Saturday at 2:20 p.m. ET, with both squads on winning streaks — three and seven in a row, respectively.The Cubs are favored at

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Swept in Japan to start the year, the Cubs split a four-game series against the Diamondbacks and then outscored the Athletics 35-9 in sweeping them in Sacramento. This three-game series is the Cubs’ first this year at Wrigley Field.

The Padres’ 7-0 record is the best of any team that the Cubs have hosted in a home opener. They have welcomed eight other teams that were unbeat